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Title : MICROWAVE MEDIATED GREEN SYNTHESIS OF SOME PYRAZOLINES AND ISOXAZOLINES
Authors : *Sonal D.Boob and PR. Solanki
Abstract : Pyrazolines and Isoxazolines have been reported to possess various activities such as analgesic, antiplatelet, antimalerial, anticancer and antiviral. Four new substituted bis benzylidiene derivative (IIIa-IIId) have been synthesized with 80-85% yield by microwave promoted condensation of ketone and aromatic aldehyde in presence of Sodium carbonate as solid phase media .A Considerable  increase in the reaction rate has been observed with better yields .The newly synthesized derivatives were treated with hydrazine hydrate and  hydroxylamine hydrochloride  to synthesize pyrazolines(IVa-d) and isoxazolines(Va-d)with neat reaction technology .The newly synthesized derivatives were characterized by  UV, IR, PMR  and elemental analysis and also screened for antimicrobial activity .

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