View                 Download                 XML
Authors : *Varun Sharma, Bharat Parashar, Abhisekh Chandel and Ajay Chandel
Abstract : The microencapsulation has a major role in solving the problems regarding targeting of drug to a specific organ tissue and controlling the rate of drug delivery to the target site. Microencapsulated drug delivery system plays a major role in developing oral controlled release systems. The objective of this work was to discuss how the efficiency of drug delivery can be increased and also how the release of drug and drug targeting can be improved. This work provides the thorough literature review of different techniques involved in microencapsulation and evaluation parameters of microencapsulation process. Various formulations were developed by using release rate controlling and gel forming polymers like HPMC-5 and HPMC-15. From among all the developed formulations, F3 formulation with HPMC-5 sustained the drug release for longer period of time as compared to other formulations. So, F3 formulation with HPMC-5 was selected as the best formulation. It was concluded that the release followed Zero order kinetics. Thus, best formulation satisfied physicochemical parameters and in vitro drug release profile requirements for a sustained drug delivery system.

A PHP Error was encountered

Severity: Notice

Message: Undefined index: HTTP_REFERER

Filename: views/issue_title.php

Line Number: 65


File: /home/pharmvmw/public_html/app_psl/views/issue_title.php
Line: 65
Function: _error_handler

File: /home/pharmvmw/public_html/app_psl/controllers/PSL.php
Line: 142
Function: view

File: /home/pharmvmw/public_html/index.php
Line: 293
Function: require_once