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Title : DEVELOPMENT AND VALIDATION OF COLORIMETRY METHOD FOR ESTIMATION OF OXCARBAZEPINE IN BULK AND TABLET DOSAGE FORM
Authors : *A. S. Shete, P. D. Lade, Snehal S. Kumbhar, A. P. Mhadeshwar, S. J. Inamdar
Abstract : A colorimetric method has been developed and validated for estimation of Oxcarbazepinein its tablet form. Ferric chloride and potassium ferricyanide were used as the coloring agents, and a yellow green color solution was formed after reaction of the drug with ferric chloride and potassium ferricyanide. The solution absorbance was measured at 735 nm. The linearity range was in the range of 1-6μg/ml. The validation of the new proposed method was carried out on various parameters like linearity, accuracy, precision, selectivity, specificity, robustness, ruggedness, LOD and LOQ.

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