||Inappropriate antibiotic use results emergence of resistance, preventable morbidity and mortality and resource
wastage. Institution based retrospective cross sectional study was conducted using patient cards and prescription
registration books to assess antibiotics utilization pattern in adult medical wards of Finote Selam Hospital (FSH). 30
cases per quarter were selected from the documented cards, based on Joint Commission on Accreditation of Health
Organizations (JCAHO) sample size recommendation. Out of 130 cards reviewed, ceftriaxone (31.02%), amoxicillin
(14.29%) and gentamicin (13.88%) were commonly prescribed. Combined antibiotics were used in 17.50% of cases
and 18.77% of prescribed antibiotics were inappropriately indicated. 53.88% of prescribed antibiotics were
administered through the intravenous route. Average number of antibiotics per encounter was 1.22 and 97.1% of
antibiotics were prescribed with generic name. 58% of antibiotics were prescribed from Essential Drug List (EDL).
Correct frequency and duration were specified in 88.16% and 42.04% of the antibiotics respectively. Duration,
dosage form, route and frequency were not specified in 57.96%, 10.20%, 8.57% and 6.53% of antibiotics
respectively. Not specifying dosage form, route, and duration; prescription habit deviating from EDL and improper
indication were problems identified. Good generic prescription habit, low level poly-pharmacy and specifying
frequency were the good practices observed.