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Title : SPECTROPHOTOMETRIC DETERMINATION OF CEFPODOXIME USING 2-HYDROXY NAPHTHALDEHYDE AS A DERIVATIZING REAGENT
Authors : M. L. Maheshwari, U. R. Mughal, Muhammad Ali Ghoto, Abdullah Dayo, Naheed Memon Mudassar Iqbal Arain, Abbas Ali
Abstract : The optimum experimental parameters for the reactions have been studied. The validity of the procedure was assessed and did not show any change in absorbance up to 24 hrs at room temperature. Statistical analysis of the result has been carried out revealing high accuracy, good precision and suitability for quality control application. The developed procedure is used for the determination of cefpodoxime in pharmaceutical formulations including tablets and suspensions. A good agreement is observed with labeled values Relative standard deviation (RSD) within 1% and recovery of the drug from pharmaceutical preparations was calculated within 95- 99.5% .

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