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Title : ANTIMICROBIAL ACTIVITY OF SELECTED HERBAL EXTRACTS AGAINST MULTI DRUG RESISTANT ORAL PATHOGENS ISOLATED FROM LEPROSY PATIENTS
Authors : Divya VV and Umamaheswari S
Abstract : Many systemic diseases reflect the poor oral health of an individual. Leprosy patients are functionally dependent and present enormous oral malformation which helps the colonization of pathogens. Oral health of leprosy patients were assessed based on the prevalence of the load of oral isolates from fifty volunteer patients. Pseudomonas sp. was found to be more prevalent in all patients which expressed a higher rate of co aggregation with other isolates (Neisseria sp., Pseudomonas sp., Staphylococcus sp., Streptococcus sp., Candida albicans and C. tropicalis). All bacterial and fungal isolates were subjected to antimicrobial sensitivity test using antibiotics and antifungal drugs recommended for oral infection (Amoxicillin, Clindamycin, Erythromycin, Penicillin G, Amphotericin B and Fluconazole) and aqueous extracts of five different herbs(Berberis aristata, Cyminum cuminum, Piper nigrum, Syzygium aromaticum, and Zingiber officinale). Berberis aristata exhibited highest antifungal activity and Syzygium aromaticum exerted highest anti bacterial activity. Hence we&nbsp; recommend the use of herbs for the preparation of choorna or oral rinse which can effectively control the colonization of multi drug resistant pathogens in the oral cavity.<br />

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