View                 Download                 XML
Authors : *Kishore Rapolu, Vinaydas Aatipamula, Kavitha Jayapala Reddy and Swathi Voruganti
Abstract : Cyclodextrins are cyclic (α -1, 4)-linked oligosaccharides of α -D-glucopyranose containing a relatively hydrophobic central cavity and hydrophilic outer surface. Cyclodextrins, which can          serve as solubilising and stabilizing agent of drug, are very significant in improving the bioavailability of drug, increasing the solubility, decreasing the stimulation, and masking the Smell. The objective of this review is to discuss and summarize some of the findings and application of novel cyclodextrin based nanocarriers.  The nanoparticles, taking cyclodextrins as the matrix, can enhance the capability of encapsuling the guest molecule; efficiently regulate the drug release rate and targeting of drug. This review also highlights the molecular structure, properties like complexation solubility, etc. of cyclodextrins and focuses on its usage in various nanocarriers like liposomes, dendrimers, carbon nanotubes, magnetic nanoparticles, gold nanoparticles and nanosponges. Thus cyclodextrins, because of their continuing ability to find several novel applications, are expected to solve many problems associated with the delivery of different novel drugs through different approaches of nanotechnology.

A PHP Error was encountered

Severity: Notice

Message: Undefined index: HTTP_REFERER

Filename: views/issue_title.php

Line Number: 65


File: /var/www/html/pharmascholars-com/app_psl/views/issue_title.php
Line: 65
Function: _error_handler

File: /var/www/html/pharmascholars-com/app_psl/controllers/PSL.php
Line: 144
Function: view

File: /var/www/html/pharmascholars-com/index.php
Line: 293
Function: require_once


A PHP Error was encountered

Severity: Core Warning

Message: Module 'soap' already loaded

Filename: Unknown

Line Number: 0