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Title : Multidrug resistant tuberculosis (MDR-TB): A lethal risk in Benghazi City, Libya
Authors : Mohamed F. Abbar; Yousef M. Sherif; Heba J. Majbri; Makarim Elfadil M. Osman and Emadeldin Hassan E. Konozy
Abstract : Anti-tuberculosis (TB) drug resistance is a major public health problem that threatens TB treatment progress made in the inhabitants of countries in Europe, Asia, Africa, and the America. A retrospective study for the pulmonary TB cases admitted to Quefia Chest Hospital Benghazi, Libya, from 1/1/2009 till 1/6/2010 showed that 4 cases out of 430 TB patients were positive for sensitivity culture and didn\'t respond to the first line anti-TB therapy and therefore were diagnosed as Multidrug Resistant Tuberculosis (MDR-TB). One of these patients was Libyan while others were aliens. The 2nd line anti-TB drugs were given in the form of Amikacin injection, cycloserine, moxifloxacin and pyrazinamide for the first 6 months followed by 18 months therapy with moxifloxacin, cycloserine and pyrazinamide. Follow-up with the patients exhibited clinical-radiological and microbiological improvement.

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