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Title : Synthesis and evaluation of 2-substituted thiadiazole Schiff bases
Authors : Chaitanya G, Jhansi G, Susmitha B, P.V. Naveen, K. N. V. Chenchu Lakshmi, B. Anupama
Abstract : A series of 1, 3, 4-thiadiazole schiff bases were synthesized and characterized by IR and 1H NMR, 13C NMR spectral data. The compounds were evaluated for antibacterial activity against gram-positive and gram-negative bacteria. Insilico screening was carried aiming to present potential selective activities as enzyme inhibitors and kinase inhibitors. These activities were suggested by the score values using molinspiration cheminformatics program.

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