||Quinazolinthione is a heterocyclic compound with a unique place in the field of medicinal chemistry. The
comprehensive study summaries the different derivative of quinazolinthione derivative along with their chemistry,
evaluated for their antibacterial activity. The structures of all newly synthesized compounds were confirmed by FTIR,
Mass spectroscopy, 1HNMR spectral data. The synthesized compound were screened for antibacterial activities
(500 μg,1000µg) against (both Gram +ve and Gram –ve) Escherichia coli, Pseudomonas aeruginosa.