||“When the gut works, use it” is a common expression used to encourage the use of the enteral route for nutrition
over the parenteral route in hospitalized patients. The same access device is often used to deliver both the enteral
formula and medications without regard to the administration site (gastric versus small bowel). Changes in drug
response as well as complications of drug administration may result from delivering enteral nutrition and medication
together through the same tube. Currently, there is no standard of practice regarding the administration of specific
medications when patients are receiving tube feeding, and if the feeding should be held for a period of time before
and after drug administration. This report provides a general review regarding interactions between enteral feeding
and the fluoroquinolones antibiotic class.