||This study was done to investigate the presence and the nature of treatment related problems in diabetic patients since it was not previously investigated. Two hundred patients were recruited in this cross sectional study. The end result is that the total number of treatment related problems was found to be 1518, with an average of 7.6 problems for each patient. The presence of actual treatment related problems as the most important determinant feature of diabetes control in out patients with diabetes. Besides four variables which were significantly associated with poor diabetes control (p= 0.05); which were: untreated condition, inappropriate adherence to medications, inappropriate adherence to clinic appointment and periodic laboratory tests, and efficacy treatment related problems.