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Title : A PROSPECTIVE STUDY ON ADVERSE DRUG REACTIONS IN A TERTIARY CARE HOSPITAL
Authors : Sindhoosha Malay, Shanmukhi.C, Rashmitha.G, Shravani.V, Venugopal.M
Abstract :

The aim of the present study was to detect and analyze the adverse drug reactions (ADRs) of antibiotics and other drugs in a tertiary care hospital. A total of 61 ADRs were reported during the study period with male predominance (51.85%) and geriatric age group. Number of ADRs was reported more from General Medicine (45.90%) and ICU (21.31%) departments in which the most affected organ systems were the GIT (34.42%), skin (18.03%) and Central Nervous System 7(11.47%). The class of drugs most commonly associated with the reported ADRs was antimicrobials 20(32.75%). The severity assessment revealed that most of them were mild level 1 (32.78%) followed by moderate and severe reactions. Of the reported reactions 57.37% of ADRs were definitely preventable, 29.50% of ADRs were probably preventable and 13.11% were not preventable. The study concluded that ADRs to antibiotics are common and less compared to other studies. Proper monitoring and reporting can ensure drug safety profile of drug.

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