Abstract

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Title ANALGESIC AND NEUROPHARMACOLOGICAL INVESTIGATIONS ON SESBANIA GRANDIFLORA
Authors Mir Muhammad Nasir Uddin, Md. Ruhul Amin, Amitabh Basak, Mohammad Shahriar
Description This study was designed to evaluate the analgesic and neurophramacological investigations of leaf extract of Sesbania grandiflora in Swiss albino mice following oral administration. In-vivo analgesic activity test was evaluated by acetic acid induced writhing method and tail immersion test. In-vivo neurophramacological investigations was determined by open field and hole cross test. In-vivo analgesic activity test shows that methanolic extract (250 & 500 mg/kg b.w.) performed good activity in mice comparing to the standard drug diclofenac Na. Methanolic extract of Sesbania grandiflora displayed a significant and dose dependent analgesic activity, the percent inhibition was 68.13%, 85.56% respectively in the test group (250 & 500 mg/kg b.w.).

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