Country-wise Listing - Brazil

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S.NO Title & Authors Name page
1
Use of the patient’s medication experience in pharmacists’ decision making process
Isabela Viana Oliveira, Erika Lourenço de Freitas, Kirla Barbosa Detoni, Djenane Ramalho-de-Oliveira
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When providing comprehensive medication management (CMM) services, pharmacists must recognize patients’ medication experiences to make patient-centered decisions. The aim of this study was to understand how patients’ medication experiences are applied in pharmacists’ decision-making process during the provision of CMM services. Using grounded theory, we devised a theoretical proposition, which derived from narratives of 11 pharmacists, observations of CMM consultations and clinical case discussions.  The results suggested that understanding the patient’s medication experiences can guide the professional to identify and resolve drug therapy problems. According to the participants, the medication experience can lead the practitioner to two courses of action: to improve health literacy, helping the patient overcome barriers to medication use; or to adapt the intervention, matching the pharmacotherapy to the patient’s routine. This knowledge can be used as a guide to teach pharmacy students and novice pharmacists how to incorporate patients’ medication experiences into clinical decision-making.

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2
LIGAND-BASED VIRTUAL SCREENING AND ADME-TOX GUIDED APPROACH TO IDENTIFY NATURAL COMPOUNDS FROM CONYZA SUMATRENSIS (RETZ.) E.H.WALKER AS COX-2 INHIBITORS
Pone Kamdem Boniface, Gouado Innocent and Anirban Pal
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The present study was intended to evaluate the anti-inflammatory activity of fractions and compounds from Conyza sumatrensis (Retz) E.K. Walker (Cs). Extracts and three compounds 1, 2 and 3 from Cs were tested for their anti-inflammatory activity through membrane red blood cell stabilisation test. In silico studies of compounds 1, 2 and 3 towards Cyclooxygenase-2 (COX-2) enzyme was performed through Autodock Vina. Cs exhibited significant anti-inflammatory activity. Among the extracts tested, ethylacetate extract was the most potent while compound 1 exhibited the highest activity among the compounds assessed. In silico studies showed that compound 3 displayed the highest binding affinity (-7.7 kcal/mol) with the target COX-2, followed by compounds 1 (-6.5 kcal/mol) and 2 (-6.1 kcal/mol). Compounds 1, 2 and 3 were also predicted free of toxicity. These results suggested that Cs might yield valuable adjunctive therapy for the treatment of inflammatory disorders.
62-70
3
INCORPORATION OF ROSEMARY (ROSMARINUS OFFICINALIS LINN.) EXTRACT IN AN ENDODONTIC SEALER: ANTIMICROBIAL EVALUATION
Marcela Agne Alves Valones, Jalber Almeida Santos, Thiago Maciel Cavalcanti, Michelly Cauás Queiroz Gatis, Arnaldo França Caldas Júnior, Eliziane Pereira Costa, Janete Magali de Araújo Alessandra de Albuquerque Tavares Carvalho
 Abstract                  View                 Download                 XML
The aim of this study is to evaluate the microbial activity of an endodontic sealer containing rosemary extract in comparison to Sealer 26. Agar well diffusion assays were used to evaluate the antimicrobial activity of the materials in the presence of the following bacterial strains: S. mutans (ATCC 25175), S. aureus (ATCC 9811) and E. faecalis (ATCC 51299). Bacterial growth inhibition halos were measured. The Mann-Whitney test was used to determine the statistical significance of differences between groups. Mean inhibition halos were 27.1, 26.4 and 38.6 mm for the strains of S. aureus, E. faecalis and S. mutans when the rosemary-based sealer was used and 16.3, 15.8 and 25.5 mm, respectively, when Sealer 26 was used. Significant differences between sealers were found for each bacterial strain (p less than 0.05). The rosemary-based endodontic sealer demonstrated greater antimicrobial efficacy in comparison to Sealer 26.
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4
IMPROVEMENT AND ASSESSMENT OF VIRTUAL PATIENT TOOL IN TEACHING OF SKILLS FOR PRACTICE OF PHARMACEUTICAL CARE
Blicie Jennifer Balisa-Rocha, Elisa Souza Menendez, Leila Maciel de Almeida e Silva, Viviane Gibara Guimaraes, Giselle de Carvalho Britto, Alessandra Rezende Mesquita, Gabriella Fernandes Magalhaes, Divaldo Pereira Lyra Junior
 Abstract                  View                 Download                 XML
In pharmacy courses, the use of virtual patients (VPs) allows students to enhance their clinical, pharmacotherapeutical, and communication skills. Therefore, to enhance and evaluate the use of the virtual patient (VP) tool — PharmaVP Software — in the teaching of skills for the practice of pharmaceutical care (PC). A methodological development study was conducted in five stages: enhancement (pre-tests), evaluation of software by developers and mentors; application; quantitative assessment, qualitative assessment, content analysis and improvement (post-tests). Nine enhancements (pre-tests) were conducted on the system. In all, 31 students resolved the clinical cases of the VP. The evaluation demonstrated that the software is functional, enables learning, and is operational, attractive, effective, productive, and satisfactory and showed positive results regarding students’acceptance, use, learning, and satisfaction. These results were confirmedby the qualitative analysis of the VP. PharmaVP Software was improved and evaluated satisfactorily for the teaching skills required for the practice of PC.
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