The objective of this study is to show the efficacy of honey as booster for the activity of antibiotics in wound healing for mothers who has done cesear section (CS) during delivery. The study was prospective study for five months. The research was conducted for mother with sepsis after 7 days from the day CS has done. There were two groups one control group who took only antibiotic (Metrondazole + ceftriaxone + dressing with normal saline) and the other group (metrondazole + ceftriaxone + honey dressing). The symptom observed during the follow up on the wound are pus, smell, pain, hotness, wound length, swelling and tenderness. The follow up was for 12 days. The average time for disappearance of each symptoms of the wound was calculated.. As a result, the average time for disapearing of the symptoms in patients under honey dressing are with much fewer days than patients without honey dressing.