Country-wise Listing - Lebanon

To view the articles from different countries, Please click on the country name on left side countries menu.
S.NO Title & Authors Name page
1
Evaluation of Gastrointestinal Complications in Lebanese Pregnant Females
Sahar Abo Rida, Sara Alzein, Jihan H. Safwan, Faraj K. Saade
 Abstract                  View                 Download                 XML
Purpose: The aim of this study is to evaluate the knowledge, awareness, and treatment of gastrointestinal complications encountered by females during gestation in Lebanon. 
Methods: A community based retrospective multicenter observational study was conducted. Information regarding frequency, severity, and treatment taken for nausea, vomiting, heartburn, and constipation in pregnant females was recorded. 
Results: We retrieved data for 381 females. The incidence of nausea and vomiting was 77.1%, of whom 53.8% had everyday symptoms and 72% had moderate to severe ones. Medical therapy was sought by 15% of the patients who were prescribed mostly pyridoxine (35.1%) and barely ondansetron (1.4%). Heartburn was reported in 70.9%, who were prescribed antacids (25.2%), histamine 2 receptor antagonists (12.1%), and proton pump inhibitors (10.2%). Constipation was encountered by 33.3% of the females and 11.8% received laxatives to lessen their symptoms. 
Conclusion: Our data show that the management is not very well understood and entails a risk in terms of adequacy and safety.
 
8-16
2
THERAPEUTIC APPROACHES FOR THE TREATMENT OF PULMONARY HYPERTENSION
*Diana Malaeb, Fouad Sakr, Mariam Dabbous
 Abstract                  View                 Download                 XML
Pulmonary hypertension is a progressive symptomatic fatal disease. It is a diagnosis of exclusion. The main goal of therapy is to lower pulmonary arterial pressure and pulmonary vascular resistance while preserving systemic pressure. Current treatments including calcium channel blockers, endothelin-1 antagonists, prostanoids, phosphodiesterase inhibitors, and prostacyclins. These treatments are palliative, may slow the progression of the disease, relief symptoms, and improve quality of life, but do not cure it. The article reviews the current updated therapeutic treatment, pharmacological action, doses, and adverse drug reaction.
436-441
3
VALIDATION OF A UV-SPECTROPHOTOMETRIC METHOD FOR THE ASSAY AND PURITY OF PARACETAMOL IN SOLUTIONS FOR IV INFUSION, AND COMPARISON OF MARKETED BRANDS
*Tabbouche O. S, Soukkariyyeh I, Naji M and Alwan T
 Abstract                  View                 Download                 XML
Paracetamol or chemically named p-acetyl-N-aminophenol is a unique analgesic and antipyretic widely used in the hospital setting all over the globe. The Paracetamol solution for IV infusion is clinically the standard analgesic in Pain Management and the first line, most safe antipyretic especially in the Pediatrics Department. According to many pharmacopoeias, the UV spectroscopy is still one of the most validated and relied on quality control assays in pharmaceutical research. Our research objective is to compare the purity and quantity of the Active Pharmaceutical Ingredient (API) &ldquo;Paracetamol&rdquo; in five different brands of Paracetamol solution for IV infusion present in the Lebanese market. The &#61548;max was 244nm in all five brands which confirms purity of the API, however Amax was the highest in Bofalgan (Bosch Pharma) and lowest in Perfumol (Hikma Pharmaceuticals). The highest concentration was observed in Perfalgan (Bristol Myers Squibb), while the lowest concentration was observed in Perfumol (Hikma Pharmaceuticals).&nbsp;&nbsp;&nbsp;&nbsp; <br />
24-27