Country-wise Listing - UAE

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S.NO Title & Authors Name page
1
THE ASSOCIATION BETWEEN CHRONIC VITAMIN D DEFICIENCY AND INCIDENCE OF TYPE 2 DIABETES MELLITUS IN ADULT POPULATION IN A TERTIARY HOSPITAL
Mubarak Nasser Al Ameri, Emad Makramalla, Umnya Albur, Anil Kumar, Ahmad Atta Sultan and Haytham Salem.
 Abstract                  View                 Download                 XML

Vitamin D, commonly known as sunshine vitamin, is both indispensable and vital for human beings. The prevalence of vitamin D deficiency (VDD) is on the rise globally including the sunny regions such as in the UAE. The aim of this study was to examine the relation between the degree of chronic vitamin D deficiency as a risk factor of the incidence of type 2 diabetes mellitus among adult populations. This is a single-centre observational retrospective cohort study conducted in a tertiary hospital in the UAE. It was mainly based on reviewing the electronic data-base and medical records of all chronic patients that match the inclusion criteria. The inclusion criteria of this study included all adult patients aged between 18 and 55 years old, tested for vitamin D level, visited the practice at least three times in the past year. The exclusion criteria included renal failure patients, patients who had malabsorption disorders and those with T2DM risk factors. A sample size of 35,000 adult patients who were screened in a period of 12 months for vitamin D level was selected using the lab database. Patients were checked against the inclusion criteria and of them, only 391 patients met the inclusion criteria. Other diabetes risk factors such as obesity, family history, pre-diabetes, presence of co-existing hypertension and dyslipidemia were also reviewed and excluded. The results of this study showed that a total of 56 patients [14% (95% CI 10.56- 17.44)] had normal results compared to 335 patients [86% (95% CI 82.56-89.44)] who had a chronic vitamin D deficiency. In addition, the results showed that 17% (95% CI 13.28- 20.72) of the 391 patients had mild vitamin D deficiency (VDD), 31% (95% CI 26.42- 35.58) moderate VDD and 38% (95% CI 33.2- 42.8) severe VDD. A total of 32% of patients with severe vitamin D deficiency developed diabetes compared to only 16% from patients with normal vitamin D deficiency and statistically showed significant difference from all other VDD groups as to developing T2DM. This indicates that the more the severity of vitamin D deficiency, the more the susceptibility to develop T2DM. Of a note, in the prevalence of severe chronic VDD, female patients showed significantly higher percentage (61%) of VDD compared to their male counterparts (39%). According to the results of this study, there is a clear relation between severe vitamin D deficiency and incidence of type 2 diabetes mellitus, whereas, mild and moderate VDD showed no difference from normal.

1010-1019
2
PREDICTORS OF PHYSICIANS ACCEPTANCE OF CLINICAL PHARMACY RECOMMENDATIONS AT A MILITARY HOSPITAL IN THE UNITED ARAB EMIRATES
Loai M. Saadah, Yazied M Nazzal, Shady I. Abdelmaksoud, Mary K. Nazzal, Eyad L. Abu Sabiha, Ayesha A. Al Qasemi
 Abstract                  View                 Download                 XML
The objective of the present work is to study the effect of a number of factors on acceptance by clinicians for clinical pharmacy recommendations. Clinical Pharmacy team documented their recommendations since June 2010 till March 2013 in a dedicated excel file. We performed univariate analyses to determine the significance of certain variables in predicting physician’s acceptance of recommendations made in 2011. Out of a total 8,451 recommendations documented in our database, 3,871 (45.3%) were made in 2011. Only 1982 (51.2 %) recommendations were fully documented with clinical pharmacist identification and therefore were available for analysis. Overall physician acceptance rate was 81.7%. Factors resulting in a higher acceptance were clinical pharmacy experience of more than 3 years (33% vs. 21%, P < 0.0001), board certification (46% vs. 37%, P = 0.002), doctor of pharmacy degree (33% vs. 21%, P < 0.0001), and post-bachelor professional education (42% vs. 32%, P = 0.001). Specialties associated with a significantly higher acceptance were critical care (21% vs. 14%, 0.002), pediatrics (12% vs. 7%, P = 0.009) and oncology (19% vs. 6%, P < 0.0001). Recommendations to stop medications were significantly more likely to be accepted (25% vs. 20%, P = 0.021). Finally, recommendations concerning antiinfectives were more likely to be accepted (26% vs. 18%, P = 0.002). Clinicians acceptance of clinical pharmacy recommendations can be predicted by variables of education, experience, specialty, medication class and type of recommendation. We recommend investing more in clinical pharmacy in the areas of critical care, pediatrics, oncology, and infectious diseases.
78-85
3
TAWAM HOSPITAL IN-PATIENT GLYCEMIC CONTROL: IT’S TIME TO STOP SLIDING
Basma Beiram
 Abstract                  View                 Download                 XML
The objective of the present work is to develop best practice for enabling targeted glycemic control in the medical and surgical setting considering the multiple factors contributing to hypo/hyperglycemia. A randomized trial comparing the safety and efficacy of a basal-bolus (BB) insulin regimen with glargine insulin once daily and aspart insulin before meals (n = 60) to sliding scale regular insulin (SSI) with regular insulin four times daily (n = 90) in patients with type 2 diabetes mellitus admitted to the medical and general surgery ward. Outcomes included differences in daily blood glucose, hospital length of stay and hypoglycemia/hyperglycemia occurrences. There was a 27% and 15% reduction in the average length of stay in the medical and surgical wards respectively post implementation of new regimen. Secondly 68% and 902% reductions in the hypoglycemic episodes per 100 patient days in the medical and surgical ward respectively post implementation of the new regimen. Basal-bolus treatment with glargine insulin once daily plus aspart insulin before meals improved glycemic control and reduced hospital complications compared with SSI in general surgery patients. Our study indicates that a basal-bolus insulin regimen is preferred over SSI in the hospital management of medical and surgery patients with type 2 diabetes.
50-56
4
ERADICATION FAILURE OF HELICOBACTER PYLORI IS RELATED TO THE NATIONALITY OF THE UNITED ARAB EMIRATES RESIDENTS IN AL AIN
Ghalia Khoder
 Abstract                  View                 Download                 XML
Helicobacter pylori (H. pylori) infection is the main cause of gastritis, peptic ulcer, gastric cancer and MALTlymphoma. H. pylori eradication has been shown to have a prophylactic effect against gastric cancer. However, the most challenging point in eradicating H. pylori is the antibiotic resistance. In the United Arab Emirates, eradication of H. pylori is based on a triple therapy regimen comprising a proton pump inhibitor and two antibiotic drugs. The aim of our study is to evaluate the eradication rate of H. pylori using this therapy regimen in infected patients (n=1000) from Hospitals and Medical centers in al Ain, United Arab Emirates during 2012. Analysis of the results using the Urea Breath Test shows a 15% eradication failure. Interestingly, Sudanese resident patients in al Ain seem to have the highest eradication failure while Filipino residents patients have a 100 % eradication success. Further studies are needed to explore the antibiotic resistance of H. pylori in the United Arab Emirates in order to cure the peptic ulcer and to avoid the progression of the infection to severe carcinogenic disease such as gastric cancer and MALT lymphoma.
133-137
5
DRUG INFORMATION IN COMMUNITY PHARMACY AND OUTPATIENT PHARMACY IN AL AIN CITY, U.A.E.: A DESCRIPTIVE STUDY
*Moawia M Al-Tabakha, Lama H Akoulah and Khairi M Fahelelbom
 Abstract                  View                 Download                 XML
The purpose of this study was to find out if the pharmacists working in community pharmacy and outpatient pharmacy have undergone any formal education regarding drug information, and to describe the drug information resources available, utilization of Internet as drug information resource and whether the available resources are sufficient to answer the types of questions received from the patients. After a pilot study, self administered eleven-question survey, open and close-ended, was distributed by a personal visit to a total of 40 pharmacies located in Al Ain city, UAE. Only one pharmacist of each visited pharmacies was eligible to complete the survey if he/she was licensed and have at least one year of experience at the same site. About 40% of the surveyed pharmacists did not have drug information resources as a course or topic in their formal education. In the pharmacies, all had the &ldquo;British National Formulary&rdquo;, followed by the &quot;Drug Information Handbook&quot;. Tertiary hospital outpatient pharmacy contained generally greater variety of drug information tertiary resources. About one third of the time spent surfing the internet was allocated for drug information. More than half of the surveyed pharmacists (55.6%) used the internet for at least 1 hour to obtain drug information. Drug safety in pregnancy and lactation was among the most frequently received questions (19.5%). The most difficult question the pharmacists received was related to the foreign drugs not available in UAE. There is a need to include a course &quot;Drug Information Resources&quot; in modern pharmacy program syllabi and to have online access to a reliable online database in the community pharmacy in order to allow the pharmacist to adequately provide accurate drug information. <br />
316-322