Rupa Gupta, P.K Sharma, Ashish Arora, Rishabha malviya <div style="text-align: justify">Taste masking is a gold standard technology  to mask the unpleasant taste of bitter active pharmaceutical ingredient. Therefore, it becomes a potential tool to improve the patient compliance & drug bioavailability. Taste masking of bitter drug using Ion exchange resin (IER) is one of the popular approaches. Ion exchange resin are cross-linked synthetic high molecular weight insoluble organic polymer having ionizable functional group. As being high molecular weight, the resin are not absorbed by the body & are therefore inert. In past few years, Ion exchange resin have since been extensively used in the drug delivery technologies included; site specific drug delivery system, Modified release dosage form, Fast dissolving tablet, clinical medicine & Biomedical application etc. The purpose of writing this review to explore the importance & application of Ion exchange resin because of their versatile properties as a taste masking technologies.</div> International Journal Of Pharmacy 2249-1848 468 2014-10-02 4 220-225 Copyright (c) Pharma Scholars. All rights reserved 2013