ANTIBACTERIAL AND ANTIOXIDANT, ANTI-INFLAMMATORY STUDY OF LEAVES AND BARK OF CASSIA FISTULA

Dinanath D. Patil, Dnyandeo K. Mhaske and Machindra Patare Gurumeet C. Wadhawa

Ethanol, methanol, chloroform and carbon tetrachloride, and hexane extracts from Cassia fistula were investigated for their in vitro antimicrobial properties, along with anti-inflammatory activity. All three extract of Cassia fistula were different in terms of their antibacterial activities. The Ethanol extract showed a stronger and broader spectrum of antibacterial activity. study was also carried out to evaluate the in-vitro antioxidant activities of ethanol, chloroform and carbon tetrachloride extract of Cassia fistula s .This was achieved by screening the two plant extracts at varying concentrations (10-50g/ml)using DPPH radical scavenging activity, reducing power assay, hydroxyl radical scavenging activity and nitric oxide radical scavenging activity. The results were analyzed statistically which showed that ethanol extract Cassia fistula had more antioxidant activity than standard antioxidant.Al extract was also studied for their anti-inflametry activity.