COMPARATIVE STUDY OF PRELIMINARY ANTIMICROBIAL ACTIVITY OF THREE DIFFERENT PLANT EXTRACTS

Mohammad Nazmul Alam*, Md. Hasibur Rahman, Md. Jainul Abeden, Md. Faruk, Md. Shahrear Biozid, Sudipta Chowdhury, Md. Rafikul Islam, Mohammed Abu Sayeed

Disk diffusion method was performed to evaluate the ex-vivo comparative study of preliminary antimicrobial activity of methanolic extract of Thunbergia grandiflora, Breynia retusa and Nymphaea capensis leaves. Among the three plants, T. grandiflora and N. capensis showed more antibacterial activity than B. retusa. T. grandiflora showed its highest activity against a gram positive bacterium Bacillus cereus with the inhibition ring of 17 mm in diameter at 1000 μg/disc. In case of B. retusa, highest activity was found against the gram negative bacterium Salmonella typhi which is 16 mm at 1000 μg/disc. N. capensis exhibited its highest antibacterial activity against the gram negative bacterium Escherichia coli which is 19 mm at 1000 μg/disc.