IN VITRO AND IN VIVO BIOLOGICAL INVESTIGATIONS OF THE WHOLE PLANT EXTRACTS OF CHROZOPHORA PROSTRATA (DALZ.)

Md. Shawkatul Islam Bakhtiar, Rumana Akhter, Syeda Najah Narjish, Sharmin Jahan Chisty, Mohammad Shahriar* and Mohiuddin Ahmed Bhuiyan

Chrozophora prostrata (Family- Euphorbiaceae), it is an herbaceous perennial plant, is found throughout Egypt, Palestine, Syria, Western Arabia, tropical Africa from Senegal to Ethiopia, South Africa (Transvaal) and tropical Asia and it is the most important herb in ayurvedic medicine. The herb has been highly valued for its traditional use as blood purifier which is also used for the treatment of chronic persistent fever, syphilis, gonorrhea, leucoderma as well as its antioxidant properties helps to maintain cell integrity. In the present study In vitro thrombolytic activity and membrane stabilizing activity, In vivo GI motility and neurophramacological activity of the whole plant extract of C. prostrata (Suryavarta, Neel kanthi, Shad, Khudi okra) was evaluated. The plant extract showed mild thrombolytic activity and membrane stabilizing activity. This plant extracts also exhibit significant GI motility and neurophramacological activity.