MEDICINAL USES AND BIOLOGICAL ACTIVITIES OF SOPHORA INTERRUPTA BEDD-A REVIEW

Pardhasaradhi Mathi, Venkata Raman Bokka and Mahendran Botlagunta*

Sophora interrupta Bedd, was a common woody perennial herb native to India. Reports suggest that the plant possesses numerous health promoting benefits such as anticancer, antiinflammatory, antimicrobial and antioxidant activities. The plant exhibited several potential in vitro anticancer effects on MCF-7, PC-3, HeLa and HePG-2 cell lines. In vivo assay’s suppressed in mouse models Dalton’s lymphoma ascites, along with acute toxicity studies, central nervous system and hepatoprotective studies. The major phytoconstituents isolated from this plant are prenylated flavonoids, chalcones, biochanin-A and Kaempferol. This review aims to concern about taxonomy, cultivation, biological activities of the isolated compounds and to evaluate the current status of S. interrupta to give a comprehensive view of its future development and further improvement of its suitability in curing a wide range of ailments.